Micro World

How small is a nuclear pore complex?

A nuclear pore complex is about 120 nm across.

What is measured: nuclear envelope channel, outer diameter

Nuclear Pore Complex (120 nm) drawn to scale beside a flu virus (100 nm) and an E. coli bacterium (2 µm)
Drawn to scale, from left to right: Flu virus (100 nm), Nuclear Pore Complex (120 nm) and E. coli bacterium (2 µm).

Compare

How big is that, really?

  • A little wider than a flu virus
  • As wide as about 5 ribosomes side by side
  • About 60× as wide as a DNA double helix

Learn

Facts about Nuclear Pore Complex

The nuclear pore complex is one of the largest protein assemblies in the cell, controlling traffic between the nucleus and cytoplasm.

Source: Molecular Biology of the Cell, Alberts et al.; Nature Reviews Molecular Cell Biology

Micro World

NameSizeCompared with Nuclear Pore Complex
Silicon Nanowire50 nm0.42×
West Nile Virus50 nm0.42×
Human Papillomavirus55 nm0.46×
Cyanophage P-SSP760 nm0.5×
Silica Nanoparticle100 nm0.83×
Titanium Dioxide Nanoparticle100 nm0.83×
Lassa Virus100 nm0.83×
Hantavirus100 nm0.83×
Nuclear Pore Complex120 nmthis page
Cowpox Virus250 nm2.1×

Test your sense of scale

Which is bigger: Nuclear Pore Complex or Silica Nanoparticle?

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